Adolescents’ cannabis use history is not an independent predictor of an elevated risk of psychosis, according to data published in the journal Adicciones.
Investigators affiliated with the University of La Rioja in Spain explored the relationship between psychotic-like experiences and cannabis use in a representative sample of over 1,500 Spanish adolescents.
They reported that initially identified associations between cannabis use and psychosis were no longer present once researchers controlled for confounding variables, such as socioeconomic status, alcohol use, tobacco smoking, and comorbid psychopathology.
Authors concluded, “In this study, it was found that after controlling for the effect of the multiple relevant co-variables, the use of cannabis was not related to the frequency and distress associated with psychotic experiences reported by adolescents. … These results suggest that the relationships established between psychotic-like experiences and cannabis are complex and mediated by relevant variables.”