CBD Dosing Modulates Brain Activity In Those At High Risk For Psychosis Per Study

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(image via Cannabis Culture)

Cannabidiol administration is associated with changes in brain activity that may potentially lower subjects’ risk for a psychotic episode, according to clinical trial data published in the journal JAMA Psychiatry.

Researchers from the United Kingdom and the Netherlands assessed the brain activating effects of a single dose of 600mg of CBD in subjects at a high risk for psychosis.

Investigators reported: “Cannabidiol may partially normalize alterations in parahippocampal, striatal, and midbrain function associated with the CHR (clinical high risk of psychosis) state. As these regions are critical to the pathophysiology of psychosis, the influence of CBD at these sites could underlie its therapeutic effects on psychotic symptoms.”

Clinical trial data has previously reported that the daily, adjunctive administration of CBD mitigates psychotic symptoms in patients with schizophrenia.

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Johnny Green
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Johnny Green is a cannabis activist from Oregon. Johnny has a bachelor's degree in public policy, and believes that the message should always be more important than the messenger. #LegalizeIt #FreeThePlant